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A Dual-Plasmid-Based CRISPR/Cas9-Mediated Strategy Enables Targeted Editing of pH Regulatory Gene pacC in a Clinical Isolate of Trichophyton rubrum

Trichophyton rubrum is the most prevalent causative agent responsible for 80–90% of all known superficial fungal infections in humans, worldwide. Limited available methods for genetic manipulations have been one of the major bottlenecks in understanding relevant molecular mechanisms of disease patho...

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Detalles Bibliográficos
Autores principales: Dey, Sanchita Sanchaya, Ramalingam, Sivaprakash, Taneja, Bhupesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782554/
https://www.ncbi.nlm.nih.gov/pubmed/36547574
http://dx.doi.org/10.3390/jof8121241