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Shock-Driven Endotheliopathy in Trauma Patients Is Associated with Leucocyte Derived Extracellular Vesicles

Endotheliopathy following trauma is associated with poor outcome, but the underlying mechanisms are unknown. This study hypothesized that an increased extracellular vesicle (EV) concentration is associated with endotheliopathy after trauma and that red blood cell (RBC) transfusion could further enha...

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Detalles Bibliográficos
Autores principales: Dujardin, Romein W. G., Kisters, Jeske E. C., Wirtz, Mathijs R., Hajji, Najat, Tuip-de Boer, Anita M., Stensballe, Jakob, Johansson, Pär I., Brohi, Karim, Davenport, Ross A., Gaarder, Christine, Stanworth, Simon, Maegele, Marc, Nieuwland, Rienk, van der Pol, Edwin, Juffermans, Nicole P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782606/
https://www.ncbi.nlm.nih.gov/pubmed/36555630
http://dx.doi.org/10.3390/ijms232415990