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Genome Organization and Copy-Number Variation Reveal Clues to Virulence Evolution in Coccidioides posadasii

The human fungal pathogen Coccidioides spp. causes valley fever, a treatment-refractory and sometimes deadly disease prevalent in arid regions of the western hemisphere. Fungal virulence in the mammalian host hinges on a switch between growth as hyphae and as large spherules containing infectious sp...

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Detalles Bibliográficos
Autores principales: Dubin, Claire A., Voorhies, Mark, Sil, Anita, Teixeira, Marcus M., Barker, Bridget M., Brem, Rachel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782707/
https://www.ncbi.nlm.nih.gov/pubmed/36547568
http://dx.doi.org/10.3390/jof8121235