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Predictive models for abdominal aortic aneurysms using polygenic scores and PheWAS-derived risk factors

Abdominal aortic aneurysms (AAA) are common enlargements of the abdominal aorta which can grow larger until rupture, often leading to death. Detection of AAA is often by ultrasonography and screening recommendations are mostly directed at men over 65 with a smoking history. Recent large-scale genome...

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Detalles Bibliográficos
Autores principales: Hellwege, Jacklyn N., Dorn, Chad, Irvin, Marguerite R., Limdi, Nita A., Cimino, James, Beasley, T. Mark, Tsao, Philip S., Damrauer, Scott M., Roden, Dan M., Velez Edwards, Digna R., Wei, Wei-Qi, Edwards, Todd L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782709/
https://www.ncbi.nlm.nih.gov/pubmed/36540997