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DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody
[Image: see text] G-quadruplexes (G4s) are four-stranded DNA secondary structures that occur in the human genome and play key roles in transcription, replication, and genome stability. G4-specific molecular probes are of vital importance to elucidate the structure and function of G4s. The scFv antib...
Autores principales: | Galli, Silvia, Melidis, Larry, Flynn, Sean M., Varshney, Dhaval, Simeone, Angela, Spiegel, Jochen, Madden, Sarah K., Tannahill, David, Balasubramanian, Shankar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782783/ https://www.ncbi.nlm.nih.gov/pubmed/36488193 http://dx.doi.org/10.1021/jacs.2c10656 |
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