Cargando…

Exploiting the DNA Damaging Activity of Liposomal Low Dose Cytarabine for Cancer Immunotherapy

Perhaps the greatest limitation for the continually advancing developments in cancer immunotherapy remains the immunosuppressive tumor microenvironment (TME). The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) axis is an emerging immunotherapy target, with the resulting type I...

Descripción completa

Detalles Bibliográficos
Autores principales: Lewicky, Jordan D., Martel, Alexandrine L., Fraleigh, Nya L., Picard, Emilie, Mousavifar, Leila, Nakamura, Arnaldo, Diaz-Mitoma, Francisco, Roy, René, Le, Hoang-Thanh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782803/
https://www.ncbi.nlm.nih.gov/pubmed/36559204
http://dx.doi.org/10.3390/pharmaceutics14122710