Cargando…

Screening and Identification of Lassa Virus Entry Inhibitors from a Fragment-Based Drug Discovery Library

Lassa virus (LASV) is a highly pathogenic virus that is categorized as a biosafety level-4 pathogen. Currently, there are no approved drugs or vaccines specific to LASV. In this study, high-throughput screening of a fragment-based drug discovery library was performed against LASV entry using a pseud...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Yuxia, Liu, Yang, Jia, Xiaoying, Zhou, Minmin, Mao, Wenting, Dong, Siqi, Zhang, Yueli, Xiao, Gengfu, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782912/
https://www.ncbi.nlm.nih.gov/pubmed/36560653
http://dx.doi.org/10.3390/v14122649