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Protofibrillar Amyloid Beta Modulation of Recombinant hCaV2.2 (N-Type) Voltage-Gated Channels

Cav2.2 channels are key regulators of presynaptic Ca(2+) influx and their dysfunction and/or aberrant regulation has been implicated in many disease states; however, the nature of their involvement in Alzheimer’s disease (AD) is less clear. In this short communication, we show that recombinant hCav2...

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Detalles Bibliográficos
Autores principales: Kaisis, Eleni, Thei, Laura J., Stephens, Gary J., Dallas, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783047/
https://www.ncbi.nlm.nih.gov/pubmed/36558910
http://dx.doi.org/10.3390/ph15121459