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A Novel Green Micellar HPLC-UV Method for the Estimation of Vandetanib in Pure Form, Human Urine, Human Plasma and Human Liver Microsomes Matrices with Application to Metabolic Stability Evaluation

Vandetanib (Caprelsa(®); VNB) is a prescription medicine that is used for the treatment of medullary thyroid cancer that has disrupted other body parts or that cannot be removed by surgery. It is considered a tyrosine kinase inhibitor (TKI). Fast, sensitive and validated HPLC–UV was established for...

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Detalles Bibliográficos
Autores principales: Alanazi, Mohammed M., Obaidullah, Ahmad J., Attwa, Mohamed W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783097/
https://www.ncbi.nlm.nih.gov/pubmed/36558172
http://dx.doi.org/10.3390/molecules27249038