Substrate Recognition Properties from an Intermediate Structural State of the UreA Transporter

Through a combination of comparative modeling, site-directed and classical random mutagenesis approaches, we previously identified critical residues for binding, recognition, and translocation of urea, and its inhibition by 2-thiourea and acetamide in the Aspergillus nidulans urea transporter, UreA....

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Detalles Bibliográficos
Autores principales: Sanguinetti, Manuel, Silva Santos, Lucianna Helene, Dourron, Juliette, Alamón, Catalina, Idiarte, Juan, Amillis, Sotiris, Pantano, Sergio, Ramón, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783183/
https://www.ncbi.nlm.nih.gov/pubmed/36555682
http://dx.doi.org/10.3390/ijms232416039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783183/
https://www.ncbi.nlm.nih.gov/pubmed/36555682
http://dx.doi.org/10.3390/ijms232416039

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