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SH2 Domains: Folding, Binding and Therapeutical Approaches

SH2 (Src Homology 2) domains are among the best characterized and most studied protein-protein interaction (PPIs) modules able to bind and recognize sequences presenting a phosphorylated tyrosine. This post-translational modification is a key regulator of a plethora of physiological and molecular pa...

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Detalles Bibliográficos
Autores principales: Diop, Awa, Santorelli, Daniele, Malagrinò, Francesca, Nardella, Caterina, Pennacchietti, Valeria, Pagano, Livia, Marcocci, Lucia, Pietrangeli, Paola, Gianni, Stefano, Toto, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783222/
https://www.ncbi.nlm.nih.gov/pubmed/36555586
http://dx.doi.org/10.3390/ijms232415944