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New Derivatives of the Multi-Stage Active Malaria Box Compound MMV030666 and Their Antiplasmodial Potencies

MMV’s Malaria Box compound MMV030666 shows multi-stage activity against various strains of Plasmodium falciparum and lacks resistance development. To evaluate the importance of its diarylether partial structure, diarylthioethers and diphenylamines with varying substitution patterns were prepared. A...

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Detalles Bibliográficos
Autores principales: Hermann, Theresa, Wallner, Robin, Dolensky, Johanna, Seebacher, Werner, Pferschy-Wenzig, Eva-Maria, Kaiser, Marcel, Mäser, Pascal, Weis, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783227/
https://www.ncbi.nlm.nih.gov/pubmed/36558954
http://dx.doi.org/10.3390/ph15121503