How Botulinum Neurotoxin Light Chain A1 Maintains Stable Association with the Intracellular Neuronal Plasma Membrane

Botulinum neurotoxin serotype A (BoNT/A) is the most potent protein toxin for humans and is utilized as a therapy for numerous neurologic diseases. BoNT/A comprises a catalytic Light Chain (LC/A) and a Heavy Chain (HC/A) and includes eight subtypes (BoNT/A1-/A8). Previously we showed BoNT/A potency...

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Detalles Bibliográficos
Autores principales: Gardner, Alexander P., Barbieri, Joseph T., Pellett, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783275/
https://www.ncbi.nlm.nih.gov/pubmed/36548711
http://dx.doi.org/10.3390/toxins14120814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783275/
https://www.ncbi.nlm.nih.gov/pubmed/36548711
http://dx.doi.org/10.3390/toxins14120814

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