Repurposing Antimalarial Pyronaridine as a DNA Repair Inhibitor to Exploit the Full Potential of Gold-Nanoparticle-Mediated Radiation Response

Radiation therapy (RT) is frequently used to locally treat tumors. One of the major issues in RT is normal tissue toxicity; thus, it is necessary to limit dose escalation for enhanced local control in patients that have locally advanced tumors. Integrating radiosensitizing agents such as gold nanopa...

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Detalles Bibliográficos
Autores principales: Jackson, Nolan, Alhussan, Abdulaziz, Bromma, Kyle, Jay, David, Donnelly, James C., West, Frederick G., Lavasanifar, Afsaneh, Weinfeld, Michael, Beckham, Wayne, Chithrani, Devika B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783290/
https://www.ncbi.nlm.nih.gov/pubmed/36559288
http://dx.doi.org/10.3390/pharmaceutics14122795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783290/
https://www.ncbi.nlm.nih.gov/pubmed/36559288
http://dx.doi.org/10.3390/pharmaceutics14122795

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