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Modeling Preeclampsia In Vitro: Polymorphic Variants of STOX1-A/B Genes Can Downregulate CD24 in Trophoblast Cell Lines

CD24 is a mucin-like immunosuppressing glycoprotein whose levels increase during pregnancy and decrease in the syncytio- and cytotrophoblasts in early and preterm preeclampsia. We used two modified cell lines that mimic in vitro features of preeclampsia to identify if this phenomenon could be reprod...

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Detalles Bibliográficos
Autores principales: Sammar, Marei, Apicella, Clara, Altevogt, Peter, Meiri, Hamutal, Vaiman, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783292/
https://www.ncbi.nlm.nih.gov/pubmed/36555567
http://dx.doi.org/10.3390/ijms232415927