Nanocrystal Preparation of Poorly Water-Soluble Drugs with Low Metal Contamination Using Optimized Bead-Milling Technology

Nanocrystal preparation using bead milling is an important technology to enhance the solubility of poorly water-soluble drugs. However, there are safety concerns regarding the metal contaminants generated during bead milling. We have previously reported optimized bead-milling parameters that could m...

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Detalles Bibliográficos
Autores principales: Tanaka, Hironori, Ochii, Yuya, Moroto, Yasushi, Hirata, Daisuke, Ibaraki, Tetsuharu, Ogawara, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783641/
https://www.ncbi.nlm.nih.gov/pubmed/36559126
http://dx.doi.org/10.3390/pharmaceutics14122633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783641/
https://www.ncbi.nlm.nih.gov/pubmed/36559126
http://dx.doi.org/10.3390/pharmaceutics14122633

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