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Nanocrystal Preparation of Poorly Water-Soluble Drugs with Low Metal Contamination Using Optimized Bead-Milling Technology

Nanocrystal preparation using bead milling is an important technology to enhance the solubility of poorly water-soluble drugs. However, there are safety concerns regarding the metal contaminants generated during bead milling. We have previously reported optimized bead-milling parameters that could m...

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Detalles Bibliográficos
Autores principales:	Tanaka, Hironori, Ochii, Yuya, Moroto, Yasushi, Hirata, Daisuke, Ibaraki, Tetsuharu, Ogawara, Ken-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783641/ https://www.ncbi.nlm.nih.gov/pubmed/36559126 http://dx.doi.org/10.3390/pharmaceutics14122633

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