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Downregulation of SMIM3 inhibits growth of leukemia via PI3K-AKT signaling pathway and correlates with prognosis of adult acute myeloid leukemia with normal karyotype

BACKGROUND: Acute myeloid leukemia (AML) patients with normal karyotype (NK-AML) have significant variabilities in outcomes. The European Leukemia Net stratification system and some prognostic models have been used to evaluate risk stratification. However, these common standards still have some limi...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Chen, Yufei, Liu, Yajun, Li, Mengya, Zhang, Yu, Shi, Luyao, Yang, Lu, Li, Tao, Li, Yafei, Jiang, Zhongxing, Liu, Yanfang, Wang, Chong, Wang, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783723/
https://www.ncbi.nlm.nih.gov/pubmed/36550462
http://dx.doi.org/10.1186/s12967-022-03831-8