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Atroposelective Amination of Indoles via Chiral Center Induced Chiral Axis Formation

The construction of an N–C chiral axis for N-aryl indole derivatives is meaningful as they widely exist in functionalized molecules. This work provides a novel method for this purpose via amination of amino acid derivatives at the C2 position of the indole and chiral center induced chiral axis forma...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Yan, Jingxue, Jiang, Yiqing, Wei, Zexuan, Tu, Zhenlin, Dong, Chao, Lu, Tao, Chen, Yadong, Feng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783779/
https://www.ncbi.nlm.nih.gov/pubmed/36558141
http://dx.doi.org/10.3390/molecules27249008