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Levels of extracellular matrix metabolites are associated with changes in Ankylosing Spondylitis Disease Activity Score and MRI inflammation scores in patients with axial spondyloarthritis during TNF inhibitor therapy

BACKGROUND/PURPOSE: In axial spondyloarthritis (axSpA) inflammation of the sacroiliac joints and spine is associated with local extracellular matrix (ECM) remodeling of affected tissues. We aimed to investigate the association of ECM metabolites with treatment response in axSpA patients treated with...

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Detalles Bibliográficos
Autores principales: Holm Nielsen, Signe, Sun, Shu, Bay-Jensen, Anne C., Karsdal, Morten, Sørensen, Inge Juul, Weber, Ulrich, Loft, Anne Gitte, Kollerup, Gina, Thamsborg, Gorm, Madsen, Ole Rintek, Møller, Jakob, Østergaard, Mikkel, Pedersen, Susanne Juhl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783808/
https://www.ncbi.nlm.nih.gov/pubmed/36564778
http://dx.doi.org/10.1186/s13075-022-02967-8