NSD1 gene evolves under episodic selection within primates and mutations of specific exons in humans cause Sotos syndrome

BACKGROUND: Modern human brains and skull shapes differ from other hominids. Brain growth disorders as micro- (ASPM, MCPH1) and macrocephaly (NFIX, GLI3) have been highlighted as relevant for the evolution in humans due to the impact in early brain development. Genes associated with macrocephaly hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Romero, Vanessa I., Arias-Almeida, Benjamin, Aguiar, Stefanie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783842/
https://www.ncbi.nlm.nih.gov/pubmed/36550402
http://dx.doi.org/10.1186/s12864-022-09071-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783842/
https://www.ncbi.nlm.nih.gov/pubmed/36550402
http://dx.doi.org/10.1186/s12864-022-09071-w

Ejemplares similares