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NSD1 gene evolves under episodic selection within primates and mutations of specific exons in humans cause Sotos syndrome
BACKGROUND: Modern human brains and skull shapes differ from other hominids. Brain growth disorders as micro- (ASPM, MCPH1) and macrocephaly (NFIX, GLI3) have been highlighted as relevant for the evolution in humans due to the impact in early brain development. Genes associated with macrocephaly hav...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783842/ https://www.ncbi.nlm.nih.gov/pubmed/36550402 http://dx.doi.org/10.1186/s12864-022-09071-w |