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Impact of Cabozantinib Exposure on Proteinuria and Muscle Toxicity in Patients with Unresectable Hepatocellular Carcinoma

This prospective study investigated the impact of cabozantinib exposure on proteinuria and muscle toxicity, in a cohort of 14 Japanese patients with unresectable hepatocellular carcinoma (uHCC). We measured the trough concentration of cabozantinib (C(trough)) weekly for 6 weeks after starting treatm...

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Detalles Bibliográficos
Autores principales: Okubo, Hironao, Ando, Hitoshi, Takasaki, Yusuke, Nakadera, Eisuke, Fukuo, Yuka, Shiina, Shuichiro, Ikejima, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783864/
https://www.ncbi.nlm.nih.gov/pubmed/36558911
http://dx.doi.org/10.3390/ph15121460