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Paricalcitol Improves the Angiopoietin/Tie-2 and VEGF/VEGFR2 Signaling Pathways in Adriamycin-Induced Nephropathy

Renal endothelial cell (EC) injury and microvascular dysfunction contribute to chronic kidney disease (CKD). In recent years, increasing evidence has suggested that EC undergoes an endothelial-to-mesenchymal transition (EndoMT), which might promote fibrosis. Adriamycin (ADR) induces glomerular endot...

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Detalles Bibliográficos
Autores principales: Deluque, Amanda Lima, Oliveira, Beatriz Magalhães, Souza, Cláudia Silva, Maciel, Ana Lívia Dias, Francescato, Heloísa Della Coletta, Giovanini, Cleonice, de Almeida, Lucas Ferreira, de Paula, Francisco José Albuquerque, Costa, Roberto Silva, Antunes-Rodrigues, José, Coimbra, Terezila Machado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783872/
https://www.ncbi.nlm.nih.gov/pubmed/36558475
http://dx.doi.org/10.3390/nu14245316