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Simultaneous Determination of Escitalopram Impurities including the R-enantiomer on a Cellulose tris(3,5-Dimethylphenylcarbamate)-Based Chiral Column in Reversed-Phase Mode

A high-performance liquid chromatographic method was developed for the simultaneous determination of the related substances—three potential synthesis-related chemical impurities and the distomer—of escitalopram. The separation capacity of seven different polysaccharide-type chiral columns, including...

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Detalles Bibliográficos
Autores principales: Szabó, Zoltán-István, Bartalis-Fábián, Ágnes, Tóth, Gergő
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783879/
https://www.ncbi.nlm.nih.gov/pubmed/36558157
http://dx.doi.org/10.3390/molecules27249022