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Thermophilic Filamentous Fungus C1-Cell-Cloned SARS-CoV-2-Spike-RBD-Subunit-Vaccine Adjuvanted with Aldydrogel(®)85 Protects K18-hACE2 Mice against Lethal Virus Challenge

SARS-CoV-2 is evolving with increased transmission, host range, pathogenicity, and virulence. The original and mutant viruses escape host innate (Interferon) immunity and adaptive (Antibody) immunity, emphasizing unmet needs for high-yield, commercial-scale manufacturing to produce inexpensive vacci...

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Detalles Bibliográficos
Autores principales: Nechooshtan, Ram, Ehrlich, Sharon, Vitikainen, Marika, Makovitzki, Arik, Dor, Eyal, Marcus, Hadar, Hefetz, Idan, Pitel, Shani, Wiebe, Marilyn, Huuskonen, Anne, Cherry, Lilach, Lupu, Edith, Sapir, Yehuda, Holtzman, Tzvi, Aftalion, Moshe, Gur, David, Tamir, Hadas, Yahalom-Ronen, Yfat, Ramot, Yuval, Kronfeld, Noam, Zarling, David, Vallerga, Anne, Tchelet, Ronen, Nyska, Abraham, Saloheimo, Markku, Emalfarb, Mark, Ophir, Yakir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783968/
https://www.ncbi.nlm.nih.gov/pubmed/36560529
http://dx.doi.org/10.3390/vaccines10122119