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Nicotinamide n-Oxide Attenuates HSV-1-Induced Microglial Inflammation through Sirtuin-1/NF-κB Signaling

HSV-1 is a typical neurotropic virus that infects the brain and causes keratitis, cold sores, and occasionally, acute herpes simplex encephalitis (HSE). The large amount of proinflammatory cytokines induced by HSV-1 infection is an important cause of neurotoxicity in the central nervous system (CNS)...

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Detalles Bibliográficos
Autores principales: Song, Xiaowei, Cao, Wenyan, Wang, Zexu, Li, Feng, Xiao, Ji, Zeng, Qiongzhen, Wang, Yuan, Li, Shan, Ye, Cuifang, Wang, Yifei, Zheng, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784159/
https://www.ncbi.nlm.nih.gov/pubmed/36555725
http://dx.doi.org/10.3390/ijms232416085