Effects of o,p’-DDE, a Mitotane Metabolite, in an Adrenocortical Carcinoma Cell Line

In South Brazil, the incidence of pediatric adrenocortical carcinoma (ACC) is higher than in other regions and countries worldwide. The ACC treatment includes therapy with mitotane, the only adrenolytic drug approved by the FDA. The mitotane metabolism occurs via two main reactions: the β-hydroxylat...

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Detalles Bibliográficos
Autores principales: Bach, Camila, Corso, Claudia Rita, Veiga, Alan de Almeida, Paraizo, Mariana Martins, de Souza, Lauro Mera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784234/
https://www.ncbi.nlm.nih.gov/pubmed/36558937
http://dx.doi.org/10.3390/ph15121486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784234/
https://www.ncbi.nlm.nih.gov/pubmed/36558937
http://dx.doi.org/10.3390/ph15121486

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