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Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling

BACKGROUND: Ovarian cancer has the highest mortality among gynecological cancers due to late diagnosis and lack of effective targeted therapy. Although the study of interplay between cancer cells with their microenvironment is emerging, how ovarian cancer triggers signaling that coordinates with imm...

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Detalles Bibliográficos
Autores principales: Lin, Sheng-Chieh, Liao, Yi-Chu, Chen, Po-Ming, Yang, Ya-Yu, Wang, Yi-Hsiang, Tung, Shiao-Lin, Chuang, Chi-Mu, Sung, Yu-Wen, Jang, Te-Hsuan, Chuang, Shuang-En, Wang, Lu-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784270/
https://www.ncbi.nlm.nih.gov/pubmed/36550569
http://dx.doi.org/10.1186/s12929-022-00888-x