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A New Gnotobiotic Pig Model of P[6] Human Rotavirus Infection and Disease for Preclinical Evaluation of Rotavirus Vaccines

Human rotavirus (HRV) is a leading cause of gastroenteritis in children under 5 years of age. Licensed vaccines containing G1P[8] and G1-4P[8] strains are less efficacious against newly emerging P[6] strains, indicating an urgent need for better cross protective vaccines. Here, we report our develop...

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Detalles Bibliográficos
Autores principales: Nyblade, Charlotte, Hensley, Casey, Parreño, Viviana, Zhou, Peng, Frazier, Maggie, Frazier, Annie, Ramesh, Ashwin, Lei, Shaohua, Degiuseppe, Juan Ignacio, Tan, Ming, Yuan, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784283/
https://www.ncbi.nlm.nih.gov/pubmed/36560807
http://dx.doi.org/10.3390/v14122803