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Landscape of Druggable Molecular Pathways Downstream of Genomic CDH1/Cadherin-1 Alterations in Gastric Cancer

Loss of CDH1/Cadherin-1 is a common step towards the acquisition of an abnormal epithelial phenotype. In gastric cancer (GC), mutation and/or downregulation of CDH1/Cadherin-1 is recurrent in sporadic and hereditary diffuse GC type. To approach the molecular events downstream of CDH1/Cadherin-1 alte...

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Detalles Bibliográficos
Autores principales: Malpeli, Giorgio, Barbi, Stefano, Innamorati, Giulio, Alloggio, Mariella, Filippini, Federica, Decimo, Ilaria, Castelli, Claudia, Perris, Roberto, Bencivenga, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784514/
https://www.ncbi.nlm.nih.gov/pubmed/36556227
http://dx.doi.org/10.3390/jpm12122006