Computational Prediction of Resistance Induced Alanine-Mutation in ATP Site of Epidermal Growth Factor Receptor

Epidermal growth factor receptor (EGFR) resistance to tyrosine kinase inhibitors can cause low survival rates in mutation-positive non-small cell lung cancer patients. It is necessary to predict new mutations in the development of more potent EGFR inhibitors since classical and rare mutations observ...

Descripción completa

Detalles Bibliográficos
Autores principales: Amelia, Tasia, Setiawan, Aderian Novito, Kartasasmita, Rahmana Emran, Ohwada, Tomohiko, Tjahjono, Daryono Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784575/
https://www.ncbi.nlm.nih.gov/pubmed/36555475
http://dx.doi.org/10.3390/ijms232415828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784575/
https://www.ncbi.nlm.nih.gov/pubmed/36555475
http://dx.doi.org/10.3390/ijms232415828

Ejemplares similares