MK2 Inhibitors as a Potential Crohn’s Disease Treatment Approach for Regulating MMP Expression, Cleavage of Checkpoint Molecules and T Cell Activity

Crohn’s Disease (CD) and Ulcerative Colitis (UC) are the two major forms of inflammatory bowel disease (IBD), which are incurable chronic immune-mediated diseases of the gastrointestinal tract. Both diseases present with chronic inflammation that leads to epithelial barrier dysfunction accompanied b...

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Detalles Bibliográficos
Autores principales: Lebish, Eric J., Morgan, Natalie J., Valentine, John F., Beswick, Ellen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784662/
https://www.ncbi.nlm.nih.gov/pubmed/36558958
http://dx.doi.org/10.3390/ph15121508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784662/
https://www.ncbi.nlm.nih.gov/pubmed/36558958
http://dx.doi.org/10.3390/ph15121508

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