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Exploring the Antimicrobial and Pharmacological Potential of NF22 as a Potent Inhibitor of E. coli DNA Gyrase: An In Vitro and In Silico Study

Toward the search for novel antimicrobial agents to control pathogenic E. coli-associated infections, a series of novel norfloxacin derivatives were screened for antimicrobial activities. The norfloxacin derivative, 1-ethyl-6-fluoro-7-(4-(2-(2-(3-hydroxybenzylidene)hydrazinyl)-2-oxoethyl)piperazin-1...

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Detalles Bibliográficos
Autores principales: Munir, Samman, Khurshid, Mohsin, Ahmad, Matloob, Ashfaq, Usman Ali, Zaki, Magdi E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784730/
https://www.ncbi.nlm.nih.gov/pubmed/36559262
http://dx.doi.org/10.3390/pharmaceutics14122768