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Hepatitis B Virus X Protein Stimulates Hepatitis C Virus (HCV) Replication by Protecting HCV Core Protein from E6AP-Mediated Proteasomal Degradation

Most clinical and experimental studies have suggested that hepatitis C virus (HCV) is dominant over hepatitis B virus (HBV) during coinfection, although the underlying mechanism remains unclear. In this study, we found that the HBV X protein (HBx) upregulates the levels of the HCV core protein to st...

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Detalles Bibliográficos
Autores principales: Yoon, Hyunyoung, Han, Jiwoo, Jang, Kyung Lib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784765/
https://www.ncbi.nlm.nih.gov/pubmed/36374094
http://dx.doi.org/10.1128/spectrum.01432-22