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Neutralization Epitopes in Trimer and Pentamer Complexes Recognized by Potent Cytomegalovirus-Neutralizing Human Monoclonal Antibodies

Human cytomegalovirus (HCMV) infects 36% to almost 100% of adults and causes severe complications only in immunocompromised individuals. HCMV viral surface trimeric (gH/gL/gO) and pentameric (gH/gL/UL128/UL130/UL131A) complexes play important roles in HCMV infection and tropism. Here, we isolated an...

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Detalles Bibliográficos
Autores principales: Ai, Yuanbao, Wu, Changwen, Zhang, Ming, Jaijyan, Dabbu Kumar, Liu, Tong, Zan, Lipeng, Li, Nan, Yu, Wei, Wang, Yueming, Yuan, Xiaohui, Li, Chengming, Zheng, Weihong, Zhu, Hua, Liao, Hua-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784774/
https://www.ncbi.nlm.nih.gov/pubmed/36342276
http://dx.doi.org/10.1128/spectrum.01393-22