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Spinal Irisin Gene Delivery Attenuates Burn Injury-Induced Muscle Atrophy by Promoting Axonal Myelination and Innervation of Neuromuscular Junctions

Muscle loss and weakness after a burn injury are typically the consequences of neuronal dysregulation and metabolic change. Hypermetabolism has been noted to cause muscle atrophy. However, the mechanism underlying the development of burn-induced motor neuropathy and its contribution to muscle atroph...

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Detalles Bibliográficos
Autores principales: Wu, Sheng-Hua, Lu, I-Cheng, Yang, Shih-Ming, Hsieh, Chia-Fang, Chai, Chee-Yin, Tai, Ming-Hong, Huang, Shu-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784798/
https://www.ncbi.nlm.nih.gov/pubmed/36555538
http://dx.doi.org/10.3390/ijms232415899