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New Insights into the Structural Requirements of Isatin-Derived Pro-Apoptotic Agents against Acute Myeloid Leukemia

Searching for bioactive compounds within the huge chemical space is like trying to find a needle in a haystack. Isatin is a unique natural compound which is endowed with different bio-pertinent activities, especially in cancer therapy. Herein, we envisaged that adopting a hybrid strategy of isatin a...

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Detalles Bibliográficos
Autores principales: Hamdy, Ahmed K., Sakamoto, Takashi, Toma, Tsugumasa, Sakamoto, Masaharu, Abourehab, Mohammed A. S., Otsuka, Masami, Fujita, Mikako, Tateishi, Hiroshi, Radwan, Mohamed O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784816/
https://www.ncbi.nlm.nih.gov/pubmed/36559030
http://dx.doi.org/10.3390/ph15121579