New Insights Regarding Hemin Inhibition of the Purified Rat Brain 2-Oxoglutarate Carrier and Relationships with Mitochondrial Dysfunction

A kinetic analysis of the transport assays on the purified rat brain 2-oxoglutarate/malate carrier (OGC) was performed starting from our recent results reporting about a competitive inhibitory behavior of hemin, a physiological porphyrin derivative, on the OGC reconstituted in an active form into pr...

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Detalles Bibliográficos
Autores principales: Miniero, Daniela Valeria, Gambacorta, Nicola, Spagnoletta, Anna, Tragni, Vincenzo, Loizzo, Stefano, Nicolotti, Orazio, Pierri, Ciro Leonardo, De Palma, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785169/
https://www.ncbi.nlm.nih.gov/pubmed/36556135
http://dx.doi.org/10.3390/jcm11247519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785169/
https://www.ncbi.nlm.nih.gov/pubmed/36556135
http://dx.doi.org/10.3390/jcm11247519

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