Distribution in Rat Blood and Brain of TDMQ20, a Copper Chelator Designed as a Drug-Candidate for Alzheimer’s Disease

(1) Background: TDMQ20 is a specific regulator of copper homeostasis in the brain, able to inhibit cognitive impairment in the early stages of Alzheimer’s disease (AD) in mouse models of AD. To promote the further development of this drug-candidate, preliminary data on the pharmacokinetics of TDMQ20...

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Detalles Bibliográficos
Autores principales: Huang, Lan, Zeng, Yaoxun, Li, Yongliang, Zhu, Yingshan, He, Yan, Liu, Yan, Robert, Anne, Meunier, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785178/
https://www.ncbi.nlm.nih.gov/pubmed/36559185
http://dx.doi.org/10.3390/pharmaceutics14122691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785178/
https://www.ncbi.nlm.nih.gov/pubmed/36559185
http://dx.doi.org/10.3390/pharmaceutics14122691

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