Synthesis and Reactions of 3-Halogenated 2-CF(3)-Indoles

Halogenation of 2-trifluoromethylindole afforded 3-chloro-, 3-bromo- and 3-iodo derivatives in up to 98% yield. Methyl-, benzyl- and tosyl-groups can be installed at the nitrogen atom of prepared indoles in high yields by base catalyzed reaction with the corresponding alkylating (sulfonylating) reag...

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Detalles Bibliográficos
Autores principales: Muzalevskiy, Vasiliy M., Sizova, Zoia A., Nenajdenko, Valentine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785211/
https://www.ncbi.nlm.nih.gov/pubmed/36557954
http://dx.doi.org/10.3390/molecules27248822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785211/
https://www.ncbi.nlm.nih.gov/pubmed/36557954
http://dx.doi.org/10.3390/molecules27248822

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