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3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents

Herein, the synthesis and anticancer activity evaluation of a series of novel β-carbolines is reported. The reactivity of nitrosoalkenes towards indole was explored for the synthesis of novel tryptophan analogs where the carboxylic acid was replaced by a triazole moiety. This tryptamine was used in...

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Detalles Bibliográficos
Autores principales: Ribeiro, João L. P., Loureiro, Joana B., Lopes, Susana M. M., Saraiva, Lucília, Pinho e Melo, Teresa M. V. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785278/
https://www.ncbi.nlm.nih.gov/pubmed/36558961
http://dx.doi.org/10.3390/ph15121510