Applications of In Silico Models to Predict Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is a major cause of the withdrawal of pre-marketed drugs, typically attributed to oxidative stress, mitochondrial damage, disrupted bile acid homeostasis, and innate immune-related inflammation. DILI can be divided into intrinsic and idiosyncratic DILI with cholestat...

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Detalles Bibliográficos
Autores principales: Lin, Jiaying, Li, Min, Mak, Wenyao, Shi, Yufei, Zhu, Xiao, Tang, Zhijia, He, Qingfeng, Xiang, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785299/
https://www.ncbi.nlm.nih.gov/pubmed/36548621
http://dx.doi.org/10.3390/toxics10120788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785299/
https://www.ncbi.nlm.nih.gov/pubmed/36548621
http://dx.doi.org/10.3390/toxics10120788

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