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Proteolysis-Targeting Chimeras (PROTACs) in Cancer Therapy: Present and Future

The PROteolysis TArgeting Chimeras (PROTACs) is an innovative technique for the selective degradation of target proteins via the ubiquitin–proteasome system. Compared with traditional protein inhibitor drugs, PROTACs exhibit advantages in the efficacy and selectivity of and in overcoming drug resist...

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Detalles Bibliográficos
Autores principales: Li, Rui, Liu, Miao, Yang, Zhenya, Li, Jiao, Gao, Yuxin, Tan, Ruirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785308/
https://www.ncbi.nlm.nih.gov/pubmed/36557960
http://dx.doi.org/10.3390/molecules27248828