Assessing the Solubility of Baricitinib and Drug Uptake in Different Tissues Using Absorption and Fluorescence Spectroscopies

The low water solubility of baricitinib (BCT) limits the development of new formulations for the topical delivery of the drug. The aims of this study were to assess the solubility of BCT in different solvents, including Transcutol, a biocompatible permeation enhancer that is miscible in water, to ev...

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Detalles Bibliográficos
Autores principales: Mohammadi-Meyabadi, Roya, Beirampour, Negar, Garrós, Núria, Alvarado, Helen Lissette, Limón, David, Silva-Abreu, Marcelle, Calpena, Ana Cristina, Mallandrich, Mireia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785369/
https://www.ncbi.nlm.nih.gov/pubmed/36559208
http://dx.doi.org/10.3390/pharmaceutics14122714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785369/
https://www.ncbi.nlm.nih.gov/pubmed/36559208
http://dx.doi.org/10.3390/pharmaceutics14122714

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