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Neuroprotective Effects of Some Nutraceuticals against Manganese-Induced Parkinson’s Disease in Rats: Possible Modulatory Effects on TLR4/NLRP3/NF-κB, GSK-3β, Nrf2/HO-1, and Apoptotic Pathways

Parkinson’s disease (PD) is a progressive neurodegenerative disorder affecting the substantia nigra where functions controlling body movement take place. Manganese (Mn) overexposure is linked to a neurologic syndrome resembling PD. Sesamol, thymol, wheat grass (WG), and coenzyme Q10 (CoQ10) are pote...

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Detalles Bibliográficos
Autores principales: Abu-Elfotuh, Karema, Hamdan, Ahmed Mohsen Elsaid, Mohammed, Asmaa A., Atwa, Ahmed M., Kozman, Magy R., Ibrahim, Amany M., Motawea, Shaimaa M., Selim, Heba Mohammed Refat M., Tohamy, Sally Tohamy Kamal, El-Din, Mahmoud Nour, Zaghlool, Sameh S., Gowifel, Ayah M. H., Awny, Magdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785377/
https://www.ncbi.nlm.nih.gov/pubmed/36559006
http://dx.doi.org/10.3390/ph15121554