IGFBP2 Drives Regulatory T Cell Differentiation through STAT3/IDO Signaling Pathway in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) represents one of the deadliest malignancies. Elevated regulatory T cell (Treg) infiltration has a potent immunosuppressive function in tumor biology, which contributes to low survival in PDAC. Nonetheless, the crosstalk between malignant cells and tumor-infil...

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Detalles Bibliográficos
Autores principales: Sun, Longhao, Zhang, Yang, Yang, Tiantian, Chen, Junhang, Zhang, Xuebin, Liang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785430/
https://www.ncbi.nlm.nih.gov/pubmed/36556226
http://dx.doi.org/10.3390/jpm12122005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785430/
https://www.ncbi.nlm.nih.gov/pubmed/36556226
http://dx.doi.org/10.3390/jpm12122005

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