Effects of SLCO1B1 Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment

Organic-anion-transporting polypeptide 1B1 (OATP1B1), encoded by the solute carrier organic anion transporter family member 1B1 gene (SLCO1B1), is highly expressed in the liver and transports several endogenous metabolites into the liver, including statins. Previous studies have not investigated the...

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Detalles Bibliográficos
Autores principales: Fernandes Silva, Lilian, Ravi, Rowmika, Vangipurapu, Jagadish, Oravilahti, Anniina, Laakso, Markku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785662/
https://www.ncbi.nlm.nih.gov/pubmed/36557197
http://dx.doi.org/10.3390/metabo12121159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785662/
https://www.ncbi.nlm.nih.gov/pubmed/36557197
http://dx.doi.org/10.3390/metabo12121159

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