The MEK Inhibitor Trametinib Improves Outcomes following Subarachnoid Haemorrhage in Female Rats

Aneurysmal subarachnoid haemorrhage (SAH) is a haemorrhagic stroke that causes approximately 5% of all stroke incidents. We have been working on a treatment strategy that targets changes in cerebrovascular contractile receptors, by blocking the MEK/ERK1/2 signalling pathway. Recently, a positive eff...

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Detalles Bibliográficos
Autores principales: Bömers, Jesper Peter, Grell, Anne-Sofie, Edvinsson, Lars, Johansson, Sara Ellinor, Haanes, Kristian Agmund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785726/
https://www.ncbi.nlm.nih.gov/pubmed/36558896
http://dx.doi.org/10.3390/ph15121446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785726/
https://www.ncbi.nlm.nih.gov/pubmed/36558896
http://dx.doi.org/10.3390/ph15121446

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