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The Effect of Losartan on Neuroinflammation as Well as on Endothelin-1- and Serotonin-Induced Vasoconstriction in a Double-Haemorrhage Rat Model

Poor patient outcome after aneurysmal subarachnoid haemorrhage (SAH) is due to a multifactorial process. Delayed cerebral vasospasm, ischemic neurological deficits, and infarction are the most feared acute sequelae triggered by enhanced synthesis of serotonin and endothelin-1 (ET-1). During the past...

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Detalles Bibliográficos
Autores principales: Konczalla, Jürgen, Mrosek, Jan, Kashefiolasl, Sepide, Musahl, Christian, Marbacher, Serge, Schubert, Gerrit Alexander, Andereggen, Lukas, Wanderer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785729/
https://www.ncbi.nlm.nih.gov/pubmed/36555984
http://dx.doi.org/10.3390/jcm11247367